This revised edition of Charles Brook's Handbook of Clinical Pediatric Endocrinology provides endocrinologists and pediatricians in training with a fully up-to-date clinical guide presenting evidence-based practice in the diagnosis, treatment, and management of pediatric endocrine disorders. New chapters include “Endocrine complications of chronic disease” and “Endocrine neoplasia.” In addition, the chapter structure has been revamped for easier access and now includes: a key points overview, multiple-choice questions for self-assessment, common errors/pitffalls (in treatment, diagnosis, etc.) boxes, a key weblinks box, a table comparing different society guidelines, diagnostic decision trees, therapeutics decision trees, and a summary. Preface , vii
List of Abbreviations, ix

1 The Relevance of Molecular Biology to Clinical Practice , 1

2 Hormones: their Nature, Action and Measurement , 15

3 The Hypothalamo-Pituitary Axis , 31

4 Endocrine Problems of Infancy , 48

5 The Management of Growth Disorders , 70

6 The Management of Puberty Disorders , 99

7 The Thyroid Gland , 129

8 The Adrenal Gland , 151

9 Disorders of Calcium and Bone Metabolism , 175

10 Water Balance , 210

11 Hypoglycemia , 230

12 Obesity and Type 2 Diabetes Mellitus , 248

13 Type 1 Diabetes Mellitus , 267

14 Endocrine Neoplasia, 296

15 Tests and Normal Values in Pediatric Endocrinology , 309

Appendix 1: Syndrome-Specific Growth Charts , 325

Appendix 2: Normal Values , 337

Index, 343
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