This new book explores clinical information in the tissue transplantation field and acts as a comprehensive learning tool to comply with regulatory requirements. Broad in scope, coverage includes all the traditionally transplanted tissues and moves into more complex areas of tissue grafting and the assisted reproduction fields. This useful text focuses on the potential for disease transmission, ways to improve safety, and the role of the clinician in these safety aspects. The book starts off by describing non-surgical risks of using allografts and moves onto chapters devoted completely to tissue- or cell-specific issues relating to transplantation of the individual types of tissues or cells.
Tissue and Cell Clinical Use: An Essential Guide is the final book in a series which covers all aspects of tissue banking, donation, processing, and transplantation. Each book in the series includes lists of learning points and case studies which consist of sample processing protocols, descriptions of where processing went wrong, sample risk assessments, or validation studies. This three book series covers all you need to know about tissue banking.
Contributor List, vii

Foreword, xiv

Preface, xvii

1 Ethical Issues Regarding the Use of Human Tissues and Cells, 1
Nikola Biller-Andorno, Diane Wilson, Ian Kerridge, and Jeremy R. Chapman

2 Clinical Governance by Physicians: Maintaining the Safety and Effectiveness of Cell and Tissue Transplantation, 23
Ted Eastlund and Ruth M. Warwick

3 Development of Vigilance and Surveillance Systems, 48
Scott A. Brubaker and Deirdre Fehily

4 Diseases Transmitted by Transplantation of Tissue and Cell Allografts, 72
Ted Eastlund and Ruth M. Warwick

5 Use of Vascular Allografts, 114
P. Dominic F. Dodd and Jeffery Dattilo

6 The Use of Allograft Heart Valves and Conduits, 135
Richard A. Hopkins, Gabriel L. Converse, and Ulrich Stock

7 The Use of Allografts in Orthopedics, 152
William W. Tomford and Eduardo J. Ortiz-Cruz

8 Neurosurgical Use of Bone Allografts and Dural Substitutes, 170
Jau-Ching Wu and Praveen V. Mummaneni

9 The Use of Allografts in Sports Medicine, 193
Scott A. Rodeo, Alexander E. Weber, René Verdonk, Joan C. Monllau, and Eva-Lisa Heinrichs

10 Allograft Tissue Used for the Practice of Dentistry, 214
Danny Holtzclaw and Tolga Fikret Tözüm

11 The Use of Allograft Skin in Burn Surgery, 236
Peter Dziewulski and Steven E. Wolf

12 Skin Substitutes: Burn Treatment and Beyond, 258
Hans-Oliver Rennekampff, Christopher R. Chapple, and Glenn Greenleaf

13 The Use of Allograft Corneas and Cells in Ophthalmic Surgery, 278
Diego Ponzin, Stefano Ferrari, Edward J. Holland, and Joseph M. Biber

14 Vascularized Composite Allotransplantation, 302
David Otterburn and Linda C. Cendales

15 The Role of Bone Marrow, Peripheral Blood Stem Cells, and Cord Blood Hemopoietic Stem Cells in Autologous, Related, and Unrelated Transplants, 312
Rachael Hough and John E. Wagner

16 Mesenchymal Stem Cells: Application for Immunomodulation and Tissue Repair, 332
Nicole J. Horwood, Francesco Dazzi, Walid Zaher, and Moustapha Kassem

17 Embryonic or Neural Stem Cells in Neurodegenerative Disease of the Central Nervous System (with Relevance to PD, HD, AD, MS, SCI, and Stroke), 358
Stephen B. Dunnett, Cesar V. Borlongan, and Paul R. Sanberg

18 Pancreatic Islet Cells, 383
Katie Kinzer, Patrick Salmon, and Jose Oberholzer

19 Stem Cells for Cardiac Repair, 403
Ranil de Silva, Amish N. Raval, and John R. Pepper

20 Use of Donated Gametes in Assisted Reproduction, 421
Tarek El-Toukhy and Mauro Costa

Index, 444

Color plate section facing p 268
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